Saline aquifers represent a promising way for CO2 sequestration. Storage capacities of saline aquifers are very important around the world. The Sleipner ,site in the North Sea is currently the single case world-wide of CO2 storage in a saline aquifer. A general review is given on the specific risks for CO2 storage in saline aquifer. The regional distribution of CO2 storage potential is presented. Finally, the knowledge gaps and the future research in this field are defined.